Powder: -20°C for 3 years In solvent: -80°C for 2 years
英文名:
α-MSH TFA
库存:
10
供应商:
TargetMol
CAS号:
171869-93-5
规格:
1 mg/10 mg/25 mg/5 mg
规格:
1 mg
产品价格:
¥498.0
规格:
10 mg
产品价格:
¥4743.0
规格:
25 mg
产品价格:
¥10582.0
规格:
5 mg
产品价格:
¥2484.0
TargetMol®所有产品仅用作科学研究,不为任何个人提供产品和服务
产品名称:α-MSH TFA 产品别名:α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
产品介绍:α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland, as well as in keratinocytes, astrocytes, monocytes, and gastrointestinal cells.1It is an agonist of melanocortin receptor 3 (MC3R) and MC4R that induces cAMP production in Hepa cells expressing the human receptors (EC50s = 0.16 and 56 nM, respectively).2α-MSH (100 pM) reducesS. aureuscolony formation andC. albicansgerm tube formationin vitro.3It inhibits endotoxin-, ceramide-, TNF-α-, or okadaic acid-induced activation of NF-κB in U937 cells.1α-MSH reduces IL-6- or TNF-α-induced ear edema in mice.4It also prevents the development of adjuvant-induced arthritis in rats and increases survival in a mouse model of septic shock. Increased plasma levels of α-MSH are positively correlated with delayed disease progression and reduced death in patients with HIV.1 纯度:N/A CAS:171869-93-5
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