- ￥6768
- AntibodySystem
- 312.5 - 20,000 ng/mL
- 25.24 ng/mL
- France
- KDD17201
- 2025年12月21日
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- 详细信息
- 技术资料
- 供应商：
武汉益普生物科技有限公司
- 检测范围：
312.5 - 20,000 ng/mL
- 检测方法：
Colorimetric
- 样本：
Plasma, Serum
- 灵敏度：
25.24 ng/mL
- 规格：
96T
| 产品名 | Ipilimumab ELISA Kit |
| 货号 | KDD17201 |
| 规格 | 96T |
| 别名 | BMS-734016, MDX-010, MDX-CTLA-4, CAS: 477202-00-9 |
| 应用 | Used for the quantitative determination of Ipilimumab concentration in serum and plasma. |
| 检测方法 | Colorimetric |
| 样本类型 | Plasma, Serum |
| 实验类型 | Quantitative |
| 检测范围 | 312.5 - 20,000 ng/mL |
| 灵敏度 | 25.24 ng/mL |
| 回收率 | 80-120% |
| 精准度 | CV<20% |
| 描述 | PRINCIPLE OF THE ASSAY This assay employs the quantitative competitive enzyme immunoassay technique. Recombinant Human CD152 has been pre-coated onto a microplate. Standards or samples are premixed with biotin-labeled antibody and then pipetted into the wells. Ipilimumab in the sample competitively binds to the pre-coated protein with biotin-labeled Ipilimumab. After washing away any unbound substances, Streptavidin-HRP is added to the wells. Following a wash to remove any unbound enzyme reagent, a substrate solution is added to the wells and color develops in inversely proportion to the amount of Ipilimumab bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| 背景 | Ipilimumab is a fully human IgG1 kappa antibody that binds to CTLA-4 (cytotoxic T lymphocyte associated antigen 4), a molecule on T cells that is indicated for unresectable or metastatic melanoma. The absence or presence of CTLA-4 can augment or suppress the immune system's T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells. The proposed mechanism of action is indirect, and may be through T-cell - mediated anti-tumor immune responses. |
| 稳定性和存储 | When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. |
| 保存方法 | 2-8 ℃ |
| 说明 | For Research Use Only. |
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Ipilimumab ELISA Kit（ELISA试剂盒）
￥6768
