- ￥6768
- AntibodySystem
- 0.31-5 μg/mL
- 0.156 μg/ml
- France
- KDJ04001
- 2025年07月07日
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- 详细信息
- 询价记录
- 技术资料
- 供应商：
武汉益普生物科技有限公司
- 检测范围：
0.31-5 μg/mL
- 检测方法：
Colorimetric
- 应用：
Quantitative
- 样本：
Plasma, Serum
- 灵敏度：
0.156 μg/ml
- 规格：
96T
| 产品名 | Enoblituzumab ELISA Kit |
| 货号 | KDJ04001 |
| 别名 | MG-A271, , CAS: 1353485-38-7 |
| 规格 | 96T |
| 检测方法 | Colorimetric |
| 样本类型 | Plasma, Serum |
| 实验类型 | Quantitative |
| 检测范围 | 0.31-5 μg/mL |
| 灵敏度 | 0.156 μg/ml |
| 回收率 | 80-120% |
| 稳定性和存储 | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
| 背景 | Enoblituzumab (also referred to as MGA271) is an Fc optimized humanized IgG1 monoclonal antibody that binds to B7-H3 (CD276), a member of the B7 family. This drug was developed by MacroGenics, Inc. that can be potentially used in the treatment of Solid tumors. Enoblituzumab is Fc-engineered with 5 amino acid substitutions to enhance binding to the activating FcγR and decrease binding to the inhibitory FcγR. Pre-clinical studies show that, in human CD16A-bearing transgenic mice, MGA271 exhibited potent antitumor activity in B7-H3–expressing xenograft models of renal cell and bladder carcinoma. To date, approximately 180 patients have received enoblituzumab monotherapy in a phase I study, with good tolerability. To determine the anti-tumor, immunological and biological effects of B7-H3 inhibition in high-risk localized pancreatic cancer, MacroGenics is currently conducting a neoadjuvant and pharmacodynamic phase II study. |
| 保存方法 | 2-8 ℃ |
| 说明 | For Research Use Only. |
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Enoblituzumab ELISA Kit（ELISA试剂盒）
￥6768
