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- 2025年12月05日
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Please store the product under the recommended conditions in the Certificate of Analysis.
- 英文名：
PPARδ/γ agonist 1
- 库存：
货期：询盘
- 供应商：
MedChemExpress LLC
- CAS号：
1257641-15-8
- 规格：
询盘
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DB-959
CAS No. : 1257641-15-8
MCE 国际站：DB-959
产品活性：DB-959 (PPARδ/γ agonist 1) 是一种有效的双重 PPAR delta/gamma 抑制剂。DB-959 可用于老年痴呆症的研究。
研究领域：Cell Cycle/DNA Damage | Vitamin D Related/Nuclear Receptor
作用靶点：PPAR
In Vivo: PPARδ/γ agonist 1 (1 mg/kg; i.g.; daily, for 16 days; STZ-mediated Long Evans rats) restores STZ-mediated impairments of motor function.
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文献和实验5.598 7.173 8.610 5 0.727 1.476 2.015 2.571 3.365 4.032 4.773 5.893 6.869 6 0.718 1.440 1.943 2.447 3.143 3.707 4.317 5.208 5.959 7 0.711 1.415 1.895 2.365 2.998 3.499 4.029 4.785 5.408 8 0.706 1.397 1.860 2.306 2.896 3.355 3.833
In Vivo Actin Polymerization ( cAMP)
a. Wash cells with DB and resuspend them to 2 X 107 / ml inDB b. Shake cells at 120 rpm for 1 hour c. Pulse cells with 100 nM cAMP for 4 hours d. Basolate cells with 3 mM caffeine for 15-30 min e. Spin cells down, add DB + 3 mM
Detection of Histone H3 Phosphorylation in Cultured Cells and Tissue Sections by Immunostaining
et al., Learn Mem 13:241–244, 2006; Wood et al., Hippocampus 15:610–621, 2005; Alarcon et al., Neuron 42:947–959, 2004; Korzus et al., Neuron 42:961–972, 2004). Stimulus-induced phosphorylation of histone H3 at serine 10 has also been implicated
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