- ￥780 - 2720
- MedChemExpress(MCE)
- 美国
- HY-150744
- 2025年12月05日
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- 文献和实验
- 技术资料
- 保存条件：
-20°C, sealed storage, away from moisture
- 库存：
货期：询盘
- 供应商：
MedChemExpress LLC
- CAS号：
1964506-30-6
- 规格：
1 mg/5 mg/10 mg
| 规格： | 1 mg | 产品价格： | ￥780.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1980.0 |
| 规格： | 10 mg | 产品价格： | ￥2720.0 |
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ODN 24888
CAS No. : 1964506-30-6
MCE 国际站：ODN 24888
产品活性：ODN 24888 是一种鸟嘌呤修饰的抑制性寡核苷酸 (INH-ODN)，对 TLR7/TLR9 介导的信号通路表现出强烈的抑制作用。ODN 24888 损害 IFN-α 水平和 NF-κB 激活，抑制 IL-6 的释放。ODN 24888 参与免疫和炎症应答，可作为疫苗佐剂使用。
作用靶点：Toll-like Receptor (TLR)
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文献和实验Antisense Efficacy: Site-Restricted In Vivo and Ex Vivo Models
In the laboratory, antisense oligodeoxynucleotides (ODN) have repeatedly demonstrated efficacy in modulating the expression of various genes, thus providing important insights into their roles in tumorigenesis or normal growth and development
Modulation of human interferon- biosynthesis by antisense oligodeoxynucleotides
We investigated the inhibition of human interferon-γ (HuIFN-γ) production in cultures of lymphocytes with the use of the antisense strategy. Out of a series of antisense oligodeoxynucleotides (ODN) complementary to different regions of the HuIFN
Transport of Antisense Across the Blood-Brain Barrier
. Recently, two types of unmodified antisense analogs have been shown to effectively cross the BBB and affect CNS function. One of the analogs, a phosphorothioate oligodeoxy-nucleotide (P-ODN) directed against the amyloid β protein, was peripherally
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