RNA-mediated interference, a gene-silencing method utilized by most eukaryotes for expression regulation and pathogen defense, provides an extremely effective research tool. Santa Cruz Biotechnology, Inc.'s siRNA Gene Silencers facilitate biological studies by selectively inhibiting expression of target proteins.
PRODUCT
Control siRNA-A is a non-targeting 20-25 nt siRNA designed as a negative control. Each vial contains lyophilized siRNA sufficient for 66 µl of 10 µM solution when resuspended as directed below. Each vial contains sufficient product for 10-20 transfections. See table below for additional fluorescein conjugated and non-conjugated siRNA controls. APPLICATIONS
Control siRNA-A is recommended as a negative control for evaluating RNAi off-target effects, and in order to verify the accuracy of gene specific siRNA-dependent RNAi.
resuspend to 66 µl, 10 µM; sufficient for 10-20 transfections
suitable as a negative control for experiments using targeted siRNA transfection
consists of a scrambled sequence that will not lead to the specific degradation of any cellular message