Distinct stage-specific transcriptional states of B cells derived from human tonsillar tissue: D.A. Espinoza, et al.; JCI Insight
8, e155199 (2023),
Abstract;
PD-1highCXCR5–CD4+ peripheral helper T cells promote CXCR3+ plasmablasts in human acute viral infection: H. Asashima, et al.; Cell Rep.
42, 111895 (2023),
Abstract;
An optimized measles virus glycoprotein-pseudotyped lentiviral vector production system to promote efficient transduction of human primary B cells: E. Vamva, et al.; STAR Protoc.
3, 101228 (2022),
Abstract;
In vitro 2D and 3D cancer models to evaluate compounds that modulate macrophage polarization: N.H. Madsen, et al.; Cell. Immunol.
378, 104574 (2022),
Abstract;
Inverse Regulation of Confluence-Dependent ADAMTS13 and von Willebrand Factor Expression in Human Endothelial Cells: M. Popa, et al.; Thromb. Haemost.
122, 611 (2022),
Abstract;
Role of CD40 ligand-mediated endothelial cell-monocyte interaction at atherosclerosis predilection sites: S. Lont, et al.; Biochem. Pharmacol.
206, 115298 (2022),
Abstract;
Quantitative assessment of NFκB transcription factor activity: T.J. Hunter, et al.; J. Immunol. Methods
2021, 112954 (2021),
Abstract;
T and B cell abnormalities, pneumocystis pneumonia, and chronic lymphocytic leukemia associated with an AIOLOS defect in patients: H.S. Kuehn, et al.; J. Exp. Med.
218, e20211118 (2021),
Abstract;
Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia: S. Zhang, et al.; J. Am. Heart Assoc.
9, e014072 (2020),
Abstract;
Full Text
C1s Inhibition by BIVV009 (Sutimlimab) Prevents Complement-Enhanced Activation of Autoimmune Human B Cells In Vitro: P.A. Nikitin, et al.; J. Immunol.
202, 1200 (2019),
Abstract;
Full Text
CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation: C. Jiang, et al.; Cell Rep.
28, 1307 (2019),
Abstract;
Full Text
Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation: L.W. Wang, et al.; Cell Metab.
30, 539 (2019),
Abstract;
Full Text
Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1: J. Kristoff, et al.; EBioMedicine
43, 295 (2019),
Abstract;
Full Text
CD40L and TNF both activate the classical NF-κB pathway, which is not required for the CD40L induced alternative pathway in endothelial cells: J. Seigner, et al.; Biochem. Biophys. Res. Commun.
495, 1389 (2018),
Abstract;
CD40L mediated alternative NFκB-signaling induces resistance to BCR-inhibitors in patients with mantle cell lymphoma: H. Rauert-Wunderlich, et al.; Cell Death Dis.
9, 86 (2018),
Abstract;
Full Text
Characterisation of anifrolumab, a fully human anti-interferon receptor antagonist antibody for the treatment of systemic lupus erythematosus: J.M. Riggs, et al.; Lupus Sci. Med.
5, e000261 (2018),
Abstract;
Full Text
Engineering protein-secreting plasma cells by homology-directed repair in primary human B cells: K.L. Hung, et al.; Mol. Ther.
26, 456 (2018),
Abstract;
High PD-L1/CD86 MFI ratio and IL-10 secretion characterize human regulatory dendritic cells generated for clinical testing in organ transplantation: A.F. Zahorchak, et al.; Cell. Immunol.
323, 9 (2018),
Abstract;
In vitro antineoplastic effects of auranofin in canine lymphoma cells: H. Zhang, et al.; BMC Cancer
18, 522 (2018),
Abstract;
Full Text
Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation: S. Infantino, et al.; Nat. Commun.
8, 891 (2017),
Application(s): B-cell activation,
Abstract;
Full Text
B-cell activation with CD40L or CpG measures the function of B-cell subsets and identifies specific defects in immunodeficient patients: E. Marasco, et al.; Eur. J. Immunol.
47, 131 (2017),
Application(s): Human PBMC culture,
Abstract;
Full Text
CD40 signaling in Graves disease is mediated through canonical and noncanonical thyroidal nuclear factor κB activation: H.J. Lee, et al.; Endocrinology
158, 410 (2017),
Abstract;
Full Text
Cutting Edge: Active TGF-β1 Released from GARP/TGF-β1 Complexes on the Surface of Stimulated Human B Lymphocytes Increases Class-Switch Recombination and Production of IgA: O. Dedo-bbeleer, et al.; J. Immunol.
199, 391 (2017),
Abstract;
Full Text
Down‐regulation of CD73 on B cells of patients with viremic HIV correlates with B cell activation and disease progression: E.S. Kim, et al.; J. Leukoc. Biol.
101, 1263 (2017),
Abstract;
Human secretory IgM emerges from plasma cells clonally related to gut memory B cells and targets highly diverse commensals: G. Magri, et al.; Immunity
47, 118 (2017),
Abstract;
Full Text
Regulation of cell surface CB2 receptor during Human B cell activation and differentiation: J.T. Castaneda, et al.; J. Neuroimmune Pharmacol.
12, 544 (2017),
Abstract;
Full Text
CD40 expression in fibrocytes Is induced by TSH: potential synergistic immune activation: T. Mester, et al.; PLoS One
11, e0162994 (2016),
Abstract;
Full Text
Distinct TLR-mediated cytokine production and immunoglobulin secretion in human newborn naïve B cells: M.A. Pettengill, et al.; Innate Immun.
22, 433 (2016),
Abstract;
Full Text
Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice: V.A. Carroll, et al.; PNAS
113, 13168 (2016),
Application(s): Human B cells culture,
Abstract;
Full Text
T-helper signals restore B-cell receptor signaling in autoreactive anergic B cells by upregulating CD45 phosphatase activity: P. Szodoray, et al.; J. Allergy Clin. Immunol.
138, 839 (2016),
Application(s): Cell culture,
Abstract;
A human monoclonal antibody targeting the conserved staphylococcal antigen IsaA protects mice against Staphylococcus aureus bacteremia: S. van den Berg, et al.; Int. J. Med. Microbiol.
305, 55 (2015),
Application(s): ELISA, PCR of human blood samples,
Abstract;
CD40L Induces Functional Tunneling Nanotube Networks Exclusively in Dendritic Cells Programmed by Mediators of Type 1 Immunity: C. Zaccard, et al.; J. Immunol.
194, 1047 (2015),
Application(s): Activation of mature human dendritic cells,
Abstract;
Detection of IκB degradation dynamics and IκB-α ubiquitination: P. Starokadomskyy, et al.; Methods Mol. Biol.
1280, 15 (2015),
Abstract;
Establishing the pig as a large animal model for vaccine development against human cancer: N.H. Overgaard, et al.; Front. Genet.
6, 286 (2015),
Abstract;
Full Text
Haploinsufficiency of the NF-κB1 subunit p50 in common variable immunodeficiency: M. Fliegauf, et al.; Am. J. Hum. Genet.
97, 389 (2015),
Abstract;
Full Text
Mechanism and functional impact of CD40 ligand-induced von Willebrand factor release from endothelial cells: K. Möller, et al.; Thromb. Haemost.
113, 1095 (2015),
Abstract;
NF-κB, p38 MAPK, ERK1/2, mTOR, STAT3 and increased glycolysis regulate stability of paricalcitol/dexamethasone-generated tolerogenic dendritic cells in the inflammatory environment: K. Danova, et al.; Oncotarget
6, 14123 (2015),
Abstract;
Full Text
Phenotypic Approaches to Identify Inhibitors of B Cell Activation: E. B. Rex, et al.; J. Biomol. Screen.
20, 876 (2015),
Application(s): Assay,
Abstract;
Full Text
Systemic agonistic anti-CD40 treatment of tumor-bearing mice modulates hepatic myeloid-suppressive cells and causes immune-mediated liver damage: J. Medina-Echeverz, et al.; Cancer Immunol. Res.
3, 557 (2015),
Abstract;
Full Text
A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo: N. Lewis, et al.; PLoS One
9, e100883 (2014),
Application(s): Assay of human PBMC,
Abstract;
Full Text
Development of a novel anti-canine CD20 monoclonal antibody with diagnostic and therapeutic potential: D. Ito, et al.; Leuk. Lymphoma
56, 219 (2014),
Application(s): Analysis of canine B-cell lymphoma cells,
Abstract;
Exosomes Derived from Burkitt’s Lymphoma Cell Lines Induce Proliferation, Differentiation, and Class-Switch Recombination in B Cells: C. Gutzeit, et al.; J. Immunol.
192, 5852 (2014),
Application(s): PCR, Assay of human B cells,
Abstract;
Full Text
Preclinical evaluation of the novel, orally bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in spontaneous canine cancer: results of a phase I study: C. London, et al.; PLoS One
9, e87585 (2014),
Application(s): Analysis of canine tumor cells by WB, FLOW,
Abstract;
Full Text
Thyrotropin receptor and CD40 mediate interleukin-8 expression in fibrocytes: implications for thyroid-associated ophthalmopathy (an American Ophthalmological Society thesis).: R. Douglas, et al.; Trans. Am. Ophthalmol. Soc.
12, 26 (2014),
Application(s): In vitro analysis of human fibrocytes,
Abstract;
Full Text
AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling: K.C. Carroll, et al.; J. Leukoc. Biol.
94, 1113 (2013),
Abstract;
Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency: F. Mazerolles, et al.; J. Allergy Clin. Immunol.
131, 1146 (2013),
Application(s): Assay of blood cells,
Abstract;
CD40 ligand is necessary and suffi cient to support primary diff use large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies: D. Ito, et al.; Leuk. Lymphoma
53, 1390 (2012),
Application(s): Flow cytometry of human B cells,
Abstract;
Full Text
HIV-1 gp120 impairs the induction of B cell responses by TLR9-activated plasmacytoid dendritic cells: N.P. Chung, et al.; J. Immunol.
189, 5257 (2012),
Application(s): Activation of dendritic cells,
Abstract;
Full Text
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency: B. Boisson, et al.; Nat. Immunol.
13, 1178 (2012),
Application(s): ELISA of human blood cells,
Abstract;
Full Text
Interleukin-6 Production in CD40-Engaged Fibrocytes in Thyroid-Associated Ophthalmopathy: Involvement of Akt and NF-κB: E.F. Gillespie, et al.; Invest. Ophthalmol. Vis. Sci.
53, 7746 (2012),
Application(s): CD40 ligation, induction and signaling in Graves' orbital fibroblasts (GOFB) and fibrocytes,
Abstract;
Full Text
Siglec-7 tetramers characterize B-cell subpopulations and leukemic blasts: F. Gieseke, et al.; Eur. J. Immunol.
42, 2176 (2012),
Application(s): ELISA of human B cells ,
Abstract;
Full Text
Stromal endothelial cells establish a bidirectional crosstalk with chronic lymphocytic leukemia cells through the TNF-related factors BAFF, APRIL and CD40L: M. Cols, et al.; J. Immunol.
188, 6071 (2012),
Application(s): UVEC & MVEC entothelial cell culture,
Abstract;
Full Text
New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein: M. Hubeau, et al.; Blood
118, 926 (2011),
Abstract;
Reconstitution of huPBL-NSG mice with donor-matched dendritic cells enables antigen-specific T-cell activation: A. Harui, et al.; J. Neuroimmune Pharmacol.
6, 148 (2011),
Application(s): Activation of dendritic cells,
Abstract;
Full Text
Study of patients with Hyper-IgM type IV phenotype who recovered spontaneously during late childhood and review of the literature: N. Karaca, et al.; Eur. J. Pediatr.
170, 1039 (2011),
Application(s): Determining human B-cell function in Hyper-IgM blood samples,
Abstract;
Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like Receptor 3 response and susceptibility to Herpes Simplex Encephalitis: R. Perez de Diego, et al.; Immunity
33, 400 (2010),
Abstract;
Multimeric soluble CD40 ligand (sCD40L) efficiently enhances HIV specific cellular immune responses during DNA prime and boost with attenuated poxvirus ventors MVA and NYVAC expressing HIV antigens : C.E. Gomez, et al.; Vaccine
27, 3165 (2009),
Abstract;
Impaired CD40L signaling is a cause of defective IL-12 and TNF-alpha production in Sezary syndrome: circumvention by hexameric soluble CD40L: L.E. French, et al.; Blood
105, 219 (2005),
Abstract;
Full Text
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex: N. Holler, et al.; Mol. Cell. Biol.
23, 1428 (2003),
Abstract;
Full Text