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Glycosyltransferase-IN-1
MCE 国际站:Glycosyltransferase-IN-1
产品活性:Glycosyltransferase-IN-1 (compound 5m) 是一种有效的糖基转移酶 (glycosyltransferase) 抑制剂,其 IC50 为 82.8 μM。Glycosyltransferase-IN-1 具有抑菌活性,对 MSSA、MRSA 和枯草杆菌的 MIC 值均为 6 μg/mL,对大肠杆菌的 MIC 值为 12 μg/mL。
研究领域:Anti-infection
作用靶点:Bacterial
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文献和实验Structural and Biochemical Analysis of a Bacterial Glycosyltransferase
Glycosyltransferases (GTs) are a large family of enzymes that specifically transfer sugar moieties to a diverse range of substrates. The process of bacterial glycosylation (such as biosynthesis of glycolipids, glycoproteins
Creation and Characterization of Glycosyltransferase Mutants of Trypanosoma brucei
suggests a minimum of 38 glycosyltransferase activities. Here we describe a functional characterization workflow in which we create glycosyltransferase null or conditional null mutants in both the bloodstream and procyclic life-cycle forms of the parasite
Glycan Microarray Screening Assay for Glycosyltransferase Specificities
Glycan microarrays represent a high-throughput approach to determining the specificity of glycan-binding proteins against a large set of glycans in a single format. This chapter describes the use of a glycan microarray platform for evaluating
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