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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
TNF
- 应用范围:
WB 1:4000
- 宿主:
Mouse
- 适应物种:
Human
- 保质期:
1-2年
- 供应商:
安诺伦(北京)生物科技有限公司
- 标记物:
Unconjugated
- 克隆性:
Monoclonal Antibody
- 保存条件:
Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态:
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
- 亚型:
IgG2a
- 免疫原:
Full length human recombinant protein of human TNF(NP_000585) produced in HEK293T cell.
- 规格:
100 ug
产品概述:Carrier-free (BSA/glycerol-free) TNF mouse monoclonal antibody, clone LBI1H3
总结:This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
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文献和实验):1532-1535. 8. Khachigian L M.Collagen antibody-induced arthritis[J].Nat Protoc,2006,1(5):2512-6. 9. Terato k,et al.Induction arthritis with monoclonal antibodies to collagen[J].J Immunol,1992,148(7):2103-8. 10. Hutamekalin P,et al.Collagen antibody
Isolation and Culture of Microvascular Endothelial Cells
by tumor necrosis factor-alpha (TNF-α) (14 ), predominantly in postcapillary venule endothelial cells (15 ), and selection of E-selectin-expressing cells by Dynabeads coupled with an anti-E-selectin monoclonal antibody.
Protocol for intracytoplasmic staining of cytokines for FACS analysis
S-2149). 7) We suggest the following antibody conjugates (usually at 10mcg/ml or as manufacturers recommendations) to detect mouse cytokines, added in saponin buffer for 30 mins at 4 deg C. I have grouped them in compatible pairs for multicolour
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