MEK3 (MAP2K3) Mouse Monoclonal Antibody [Clone ID: LBI5C9]

MEK3 (MAP2K3) Mouse Monoclonal

Antibody [Clone ID: LBI5C9]
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  • ¥3300
  • Leading Biology
  • 美国
  • 2025年07月11日
  • WB 1:200~2000, IF 1:100
  • Mouse
  • Human, Mouse, Rat, Dog
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    • 详细信息
    • 技术资料
    • 靶点

      MAP2K3

    • 应用范围

      WB 1:200~2000, IF 1:100

    • 宿主

      Mouse

    • 适应物种

      Human, Mouse, Rat, Dog

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

    • 亚型

      IgG2b

    • 免疫原

      Full length human recombinant protein of human MAP2K3(NP_659731) produced in HEK293T cell.

    • 规格

      100 ug

    别名:MAPKK3; MEK3; MKK3; PRKMK3; SAPKK-2; SAPKK2

    产品概述:Carrier-free (BSA/glycerol-free) MAP2K3 mouse monoclonal antibody, clone LBI5C9

    总结:The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]

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