PSMC3 Mouse Monoclonal Antibody [Clone ID: LBI8D6]

PSMC3 Mouse Monoclonal Antibod

y [Clone ID: LBI8D6]
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  • ¥3300
  • Leading Biology
  • 美国
  • 2025年07月12日
  • WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100
  • Mouse
  • Human, Mouse, Rat
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    • 详细信息
    • 技术资料
    • 靶点

      PSMC3

    • 应用范围

      WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100

    • 宿主

      Mouse

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

    • 亚型

      IgG1

    • 免疫原

      Full length human recombinant protein of human PSMC3(NP_002795) produced in HEK293T cell.

    • 规格

      100 ug

    别名:DCIDP; RPT5; TBP1

    产品概述:Carrier-free (BSA/glycerol-free) PSMC3 mouse monoclonal antibody, clone LBI8D6

    总结:The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

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