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FKBP12 (FKBP1A) Mouse Monoclon

al Antibody [Clone ID: LBI3B3]
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  • ¥3300
  • Leading Biology
  • 美国
  • 2025年07月12日
  • WB: 1:200 - 1:1000, IHC 1:150, FLOW 1:100
  • Mouse
  • Human, Mouse, Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 靶点

      FKBP1A

    • 应用范围

      WB: 1:200 - 1:1000, IHC 1:150, FLOW 1:100

    • 宿主

      Mouse

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

    • 亚型

      IgG2b

    • 免疫原

      Full length human recombinant protein of human FKBP1A (NP_000792) produced in HEK293T cell.

    • 规格

      100 ug

    别名:FKBP-1A; FKBP-12; FKBP1; FKBP12; PKC12; PKCI2; PPIASE

    产品概述:Carrier-free (BSA/glycerol-free) FKBP1A mouse monoclonal antibody, clone LBI3B3

    总结:The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq]

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    图标文献和实验
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