Neuroserpin (SERPINI1) Mouse M

别名：HNS-S1; HNS-S2; neuroserpin; PI12

产品概述：Carrier-free (BSA/glycerol-free) SERPINI1 mouse monoclonal antibody,clone LBI1A5

总结：This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]