手机验证
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FRTL 5; FRTL5; FRTL-5 Cl 2
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充足
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Fischer
甲状腺
大鼠甲状腺细胞
大鼠
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上皮细胞样
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甲状腺
复苏发货或干冰冷冻发货
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粘附,具有凸起中心的团块
1 x 10^6 cells/vial/T25
细胞名称:FRTL-5大鼠甲状腺细胞
产品货号:C3104
描述:FRTL-5 细胞源自5至6周龄 Fischer 大鼠的甲状腺,与其他细胞系不同,FRTL-5 细胞倾向于以复杂的三维结构生长,而不是形成单层,为研究甲状腺细胞行为提供了独特的模型。大鼠品系:Fischer。
培养条件:推荐WHELAB自配培养基:
※ Leibovitz's L-15(货号:M0800)+ 10%胎牛血清
※ 配套完全培养基:(货号:M0801)
温度:37℃
气相:100%空气
生长特性:粘附,具有凸起中心的团块
细胞形态:上皮细胞样
产品规格:1 x 10^6 cells/vial/T25
冻存条件:细胞保存液(货号:G0200)
保存条件:液氮存储
用户须知:
1、关于货期:除复苏细胞外,承诺货期1周内到(节假日顺延),大多数产品1-3天内发货。细胞产品因需要复苏后进行1-2代传代调整后等待细胞长满,期间进行微生物检测,货期1、2周左右。
2、关于订购:为了保证您的权益,下单前务必联系我司客户服务热线(021-55150076)。
安全性:
所有肿瘤和病毒转染的细胞均视为有潜在的生物危害性,必须在二级生物安全台内操作,并请注意防护。
公司简介:
WheLab 是一家位于上海的高新技术公司,专注于细胞培养和分子生物学资源开发,服务于各大科研院校、医院和医药企业。 公司拥有先进的分子实验室、细胞培养间、液氮罐,收藏了1000+ 种细胞系,来源于ATCC细胞,DSMZ细胞,JCRB细胞,RIKEN细胞,ScienCell细胞等机构。同时包含自主研发建系的各类示踪细胞、耐药株、基因敲除细胞等。实验室可配制基础实验所需的常规试剂,实验室管理规范,细胞株均有STR鉴定和支原体检测,质量保证! 我们拥有国内、美国海归等丰富经验与专业技术的精英团队,秉承“专业、诚信、可靠”为公司宗旨,以合理的价格,完善的服务,提供可靠的产品,为广大客户提供完整的生物细胞技术解决方案。
如果您需要进一步的信息和服务,欢迎联系我们。
联系人:童小姐
电话:15921090068(微信同号)
:2306932016
:021-55150076
官网:https://whelab.com
公司邮箱:info@whelab.com
技术邮箱:tech@whelab.com
地址:上海宝山区呼兰西路129号8号楼4层
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
PubMed=6327870; DOI=10.1677/joe.0.1010269
Bidey S.P., Chiovato L., Day A., Turmaine M., Gould R.P., Ekins R.P., Marshall N.J.
Evaluation of the rat thyroid cell strain FRTL-5 as an in-vitro bioassay system for thyrotrophin.
J. Endocrinol. 101:269-276(1984)
Patent=US4608341
Ambesi-Impiombato F.S.
Living, fast-growing thyroid cell strain, FRTL-5.
Patent number US4608341, 26-Aug-1986
PubMed=2868604; DOI=10.1530/acta.0.1110054
Brandi M.L., Rotella C.M., Zonefrati R., Toccafondi R., Aloj S.M.
Loss of adrenergic regulation of cAMP production in the FRTL-5 cell line.
Acta Endocrinol. 111:54-61(1986)
PubMed=3475907; DOI=10.1530/acta.0.114s242
Ambesi-Impiombato F.S., Villone G.
The FRTL-5 thyroid cell strain as a model for studies on thyroid cell growth.
Acta Endocrinol. 116 Suppl. 281:242-245(1987)
PubMed=3670314; DOI=10.1128/mcb.7.9.3365-3370.1987
Fusco A., Berlingieri M.T., Di Fiore P.P., Portella G., Grieco M., Vecchio G.
One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes.
Mol. Cell. Biol. 7:3365-3370(1987)
PubMed=2545492; DOI=10.1016/0303-7207(89)90020-8
Sugawa H., Mori T., Imura H.
Establishment of 8-azaguanine-resistant mutants from rat thyroid cell line FRTL-5.
Mol. Cell. Endocrinol. 62:319-326(1989)
PubMed=2551628; DOI=10.1210/endo-125-4-1783
Pang X.-P., Hershman J.M., Chung M., Pekary A.E.
Characterization of tumor necrosis factor-alpha receptors in human and rat thyroid cells and regulation of the receptors by thyrotropin.
Endocrinology 125:1783-1788(1989)
PubMed=1694496; DOI=10.1210/endo-127-1-419
Ossendorp F.A., Bruning P.F., Schuuring E.M.D., van den Brink J.A.M., van der Heide D., de Vijlder J.J.M., de Bruin T.W.A.
Thyrotropin dependent and independent thyroid cell lines selected from FRTL-5 derived tumors grown in nude mice.
Endocrinology 127:419-430(1990)
CLPUB00429
Gerber H., Peter H.-J., Bosiger J., Studer H., Drews R., Ferguson D.C., Peterson M.E., Becker D.V.
Different continuous cell lines from adenomatous feline goiters widely differ in morphologic, functional and growth parameters.
(In) Progress in thyroid research. Proceedings of the 10th International Thyroid Conference; Gordon A., Gross J., Hennemann G. (eds.); pp.541-544; A A Balkema Publishers; Rotterdam (1991)
CLPUB00430
Peter H.-J., Gerber H., Studer H., Groscurth P., Zakarija M.
Thyroid cell lines forming follicle-like lumina in vitro.
(In) Progress in thyroid research. Proceedings of the 10th International Thyroid Conference; Gordon A., Gross J., Hennemann G. (eds.); pp.579-582; A A Balkema Publishers; Rotterdam (1991)
PubMed=1726925
Gerber H., Peter H.-J., Asmis L., Studer H.
Thyroid cell lines in research on goitrogenesis.
Thyroidology 3:115-118(1991)
PubMed=1846098; DOI=10.1210/endo-128-1-211
Peter H.-J., Gerber H., Studer H., Groscurth P., Zakarija M.
Comparison of FRTL-5 cell growth in vitro with that of xenotransplanted cells and the thyroid of the recipient mouse.
Endocrinology 128:211-219(1991)
PubMed=7836899; DOI=10.1677/joe.0.1430527
MacNeil S., Munro D.S., Metcalfe R., Cotterell S., Ruban L., Davies R., Weetman A.P.
An investigation of the ability of TSH and Graves' immunoglobulin G to increase intracellular calcium in human thyroid cells, rat FRTL-5 thyroid cells and eukaryotic cells transfected with the human TSH receptor.
J. Endocrinol. 143:527-540(1994)
PubMed=7912172; DOI=10.1111/j.1365-2265.1994.tb03017.x
Michelangeli V.P., Munro D.S., Poon C.W., Frauman A.G., Colman P.G.
Measurement of thyroid stimulating immunoglobulins in a new cell line transfected with a functional human TSH receptor (JPO9 cells), compared with an assay using FRTL-5 cells.
Clin. Endocrinol. (Oxf.) 40:645-652(1994)
PubMed=8761378; DOI=10.1038/bjc.1996.409
van der Kallen C.J.H., Coes J.H., van Grafhorst J.P., Schuuring E.M.D., Ossendorp F.A., Thijssen J.H.H., Blankenstein M.A., de Bruin T.W.A.
Dissociation of thyrotropin receptor function and thyrotropin dependency in rat thyroid tumour cell lines derived from FRTL-5.
Br. J. Cancer 74:606-612(1996)
PubMed=9709917; DOI=10.1089/thy.1998.8.623
Tasevski V., Benn D., Peters G., Luttrell B., Simpson A.
The Fischer rat thyroid cell line FRTL-5 exhibits a nondiploid karyotype.
Thyroid 8:623-626(1998)
PubMed=20151827; DOI=10.1089/thy.2009.0171
Sebai H., Hovsepian S., Ristorcelli E., Aouani A., Lombardo D., Fayet G.
Resveratrol increases iodide trapping in the rat thyroid cell line FRTL-5.
Thyroid 20:195-203(2010)
PubMed=21087161; DOI=10.1089/ast.2010.0461
Albi E., Ambesi-Impiombato F.S., Villani M., De Pol I., Spelat R., Lazzarini R., Perrella G.
Thyroid cell growth: sphingomyelin metabolism as non-invasive marker for cell damage acquired during spaceflight.
Astrobiology 10:811-820(2010)
DOI=10.1128/mcb.00663-17
Fusco A., Berlingieri M.T., Di Fiore P.P., Portella G., Grieco M., Vecchio G.
Retraction for Fusco et al., 'One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes'.
Mol. Cell. Biol. 38:e00663.17.1-e00663.17.1(2018)
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