3,5,6,7,8,3',4'-Heptamethoxyflavone (HMF) is a polymethoxyflavone that has been found in C. reticulata and has diverse biological activities.{25346,61964,52726,61965} It inhibits the efflux of Hoechst 33342 (Item No. 15547) by breast cancer resistance p
英文名:
HMF|NSC 618928
库存:
1 mg, 5 mg
供应商:
Cayman
CAS号:
1178-24-1
规格:
This biochemical is available in the following size(s) 10 mg, 5 mg - Please inquire
A polymethoxyflavone; inhibits the efflux of Hoechst 33342 by BCRP and rhodamine 123 by P-gp in MDCK cells expressing the human transporters (IC50s = 1.4 and 31 µM, respectively); prevents UVB-induced decreases in type I procollagen in HDFn cells at 50, 100, and 200 µg/ml; inhibits the proliferation of B16 melanoma 4A5, CCRF-HSB-2 leukemia, and TGBC11TKB gastric cancer cells (IC50s = 38, 29, and 9 µM, respectively); prevents corticosterone-induced increases in immobility time in the forced swim test in mice at 50 mg/kg