TVB-2640 is an inhibitor of fatty acid synthase (FASN; IC50 = 0.5 µM).{66010} It inhibits infection of an infectious-clone-derived severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reporter virus in HEK293T cells expressing human angiotensin-
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A FASN inhibitor (IC50 = 0.5 µM); inhibits infection of an infectious-clone-derived SARS-CoV-2 reporter virus in HEK293T cells expressing human ACE2 (EC50 = 4 nM)