Lipoamide is an amide derivative of lipoic acid (Item No. 10005728).{65270} It is an essential cofactor for enzymes in the citric acid cycle and enzymes involved in the catabolism of glycine and branched-chain amino acids (BCAAs).{65271} Lipoamide is co
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An amide derivative of lipoic acid; an essential cofactor for enzymes in the citric acid cycle and enzymes involved in the catabolism of glycine and BCAAs; reduces hydrogen peroxide- or 6-OHDA-induced cytotoxicity in PC12 cells at 50 and 100 µM; reverses mitochondrial dysfunction, increases the number of midbrain dopaminergic neurons, and improves fine motor activity in a rat model of 6-OHDA-induced Parkinson’s disease at 100 mg/kg