- ￥1855
- 翌圣生物（Yeasen）
- 上海
- 90180ES10
- 2025年12月07日
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- 详细信息
- 文献和实验
- 技术资料
- 保质期：
有效期1年
- 保存条件：
-20℃至-80℃保存
- 英文名：
Recombinant Rat Interleukin-33 (Rat IL-33)
- 库存：
大量
- 供应商：
翌圣生物科技（上海）股份有限公司
- 规格：
10μg
Product Information
| Product Name |
Cat# |
Size |
Price（¥） |
| Recombinant Rat Interleukin-33 (Rat IL-33) |
90180ES10 |
10 μg |
1,855 |
| 90180ES60 |
100 μg |
13,615 |
|
| 90180ES76 |
500 μg |
35,395 |
Product Description
IL-33 (Interleukin-33) is released from physically damaged or necrotic cells. It triggers Th2-biased immune cell activation at sites of inflammation as well as regulatory T cell and M2 macrophage expansion. It additionally induces angiogenesis, promotes tumor cell migration and invasion, limits cardiac myocyte hypertrophy, and limits the development of atherosclerotic plaques. IL-33 signals through a receptor complex composed of ST2 and IL-1 RAcP. IL-1 RAcP also associates with IL-1 RI, IL-1 RII, IL-1 R6, and SCF R/c-kit. Soluble isoforms of ST2 and IL-1 RAcP function as decoy receptors that regulate IL-33 bioactivity.
Product Properties
| Synonyms |
IL-33 |
| Accession |
|
| GeneID |
|
| Source |
E.coli-derived Rat IL-33, Ser109-Met264. |
| Molecular Weight |
Approximately 17.4 kDa. |
| AA Sequence |
SIQGTSLLTE SCALSTYNDQ SVSFVLENGC YVINVEDCGK NQEKDKVLLR YYESSFPAQS GDGVDGKKLM VNMSPIKDTD IWLNANDKDY SVELQKGDVS PPDQAFFVLH KKSSDFVSFE CKNLPGTYIG VKDNQLALVE ENDESCNNIM FKLSKM |
| Tag |
None |
| Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity |
> 95% by SDS-PAGE and HPLC analyses. |
| Biological Activity |
The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 0.5 ng/mL, corresponding to a specific activity of > 2.0 × 106 IU/mg. Fully biologically active when compared to standard. |
| Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
| Formulation |
Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM Tris, 300 mM NaCl, pH 8.5. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only!
HB220425
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文献和实验白细胞介素 IL-33 IL-33主要产生细胞：黏膜等多种组织细胞 IL-33氨基酸数目：270／266 IL-33分子质量(kDa)：30／29．9 IL-33受体：IL-1受体；ST2 IL-33主要生物学活性：激活NFκB和MAPK途径，促进Th2细胞表达IL-4、1D5和IL-l3
小鼠白细胞介素33（IL-33） 酶联免疫 分析 试剂 盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定小鼠血清，血浆及相关液体样本中白细胞介素33（IL-33）的含量。 实验原理 ： 本试剂盒应用双抗体夹心法测定 标本 中 小鼠白细胞介素33 （ IL-33 ） 水平。用纯化的 小鼠白细胞介素33 （ IL-33 ） 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 白细胞介素33 （ IL-33
人 白细胞介素33(IL-33) 酶联免疫 分析（ ELISA ） 试剂 盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中白细胞介素33(IL-33) 的 含量。 实验原理 ： 本试剂盒应用双抗体夹心法测定 标本 中 人白细胞介素33(IL-33) 水平。用纯化的 白细胞介素33(IL-33) 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 白细胞介素33(IL-33
