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| 规格： | 10 mM * 1 mL | 产品价格： | ￥3190.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥2900.0 |
| 规格： | 10 mg | 产品价格： | ￥4650.0 |
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Immunoproteasome inhibitor 1
CAS No. : 2755772-63-3
MCE 国际站：Immunoproteasome inhibitor 1
产品活性：Immunoproteasome inhibitor 1 是一种有效的、可逆的、依时独立的免疫蛋白酶体 (immunoproteasome) 和蛋白酶体 (proteasome) 抑制剂 (β5c、β1i、β5i亚基的Kis分别为1.18、0.27、1.91 μM)。Immunoproteasome inhibitor 1 可用于研究一些肿瘤性疾病。
研究领域：Metabolic Enzyme/Protease
作用靶点：Proteasome
In Vitro: Immunoproteasome inhibitor 1 (compound 9) (0-25 μM; 0-600 seconds; in Human 20S immunoproteasome and human 20S proteasome) has high binding affinity for the β1i subunit (0.27 µM) of immunoproteasome and proteasome, coupling with good inhibitory properties towards β5i and β5c subunits. And the results of against the β5i subunit shows that the inhibition is reversible, time-independent.
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文献和实验Osteoblast-like Cells Objective: To characterize the effects of E2 on the expression of matrix metalloproteinases (MMPs) and tissue inhibitor of matrix metalloproteinases (TIMPs) in human osteosarcoma cell line MG-63 and normal human osteoblast(hOB
correct reconstruction of A53T and A30P.（8）结果:DNA测序结果证明构建载体插入正确α-突触核蛋白突变体A53T与A30P基因。（9）METHODS: RKO cells were treated with selective DNA methyltransferase (DNMTs) inhibitor, 5-Aza-2′-deoxycytidine (5-Aza-CdR), for 72 h. Methylation-specific PCR (MSP), T
浅析染色质免疫沉淀（ChIP）技术在 DNA 与蛋白质相互作用研究中的重要性
analysis reveals genes associated with the ability of MYC to maintain tumorigenesis. PLoS Genet, 2008. 4(6): p. e1000090. [6] Guo, H., et al., Tissue factor pathway inhibitor-2 was repressed by CpG hypermethylation through inhibition of KLF6 binding
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