产品概述:Recombinant protein of human syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) (SNTA1)蛋白长度:Recombinant protein was produced with GoldORF clone, [GH34418V]. Click on the GoldORF clone link to view cDNA and protein sequences.表达系统:HEK293T种属:Human标签类型:C-Myc/DDK分子量:53.7 kDa通用名:SNTA1总结:Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013]形式:Liquid浓度:>50 ug/mL as determined by microplate BCA method纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol别名:dJ1187J4.5; LQT12; SNT1; TACIP1