产品概述:Recombinant protein of human cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1)蛋白长度:Recombinant protein was produced with GoldORF clone, [GH35683V]. Click on the GoldORF clone link to view cDNA and protein sequences.表达系统:HEK293T种属:Human标签类型:C-Myc/DDK分子量:58 kDa通用名:CYP1A1总结:This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]形式:Liquid浓度:>50 ug/mL as determined by microplate BCA method纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol别名:AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX