beta Catenin (CTNNB1) (NM_0019

产品概述：Recombinant protein of human catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1) 蛋白长度：Recombinant protein was produced with GoldORF clone, [GH38802V]. Click on the GoldORF clone link to view cDNA and protein sequences. 表达系统：HEK293T 种属：Human 标签类型：C-Myc/DDK 分子量：85.3 kDa 通用名：CTNNB1 总结：The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol 别名：armadillo; CTNNB; EVR7; MRD19; NEDSDV