产品概述:Recombinant protein of human splicing factor 3b, subunit 3, 130kDa (SF3B3)蛋白长度:Recombinant protein was produced with GoldORF clone, [GH39351V]. Click on the GoldORF clone link to view cDNA and protein sequences.表达系统:HEK293T种属:Human标签类型:C-Myc/DDK分子量:135.4 kDa通用名:SF3B3总结:This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]形式:Liquid浓度:>50 ug/mL as determined by microplate BCA method纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol别名:RSE1; SAP130; SF3b130; STAF130