产品概述:Purified recombinant protein of Human serum amyloid A1 (SAA1), transcript variant 1, 19Arg-End, with N-terminal HIS tag, expressed in E.Coli, 50 ug蛋白长度:A DNA sequence encoding the region(19Arg-End) of SAA1表达系统:E. coli种属:Human标签类型:N-HIS分子量:11.7KDa通用名:SAA1总结:This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Jul 2020]形式:Liquid浓度:>50 ug/mL as determined by microplate BCA method纯度:> 90% as determined by SDS-PAGE and Coomassie blue staining储存溶液:25 mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.别名:PIG4; SAA; SAA2; TP53I4