Ecd (NM_027475) Mouse Recombin

产品概述：Purified recombinant protein of Mouse ecdysoneless cell cycle regulator (Ecd), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug 蛋白长度：A DNA sequence from Mouse cDNA ORF Clone, [GM38955V], encoding Mouse full-length Ecd. 表达系统：HEK293T 种属：Mouse 标签类型：C-MYC/DDK 分子量：71.7 kDa 通用名：Ecd 总结：Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes (By similarity). Involved in regulation of cell cycle progression (PubMed:26711270). Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839). The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing (By similarity).[UniProtKB/Swiss-Prot Function] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. 别名：5730461K03Rik; Hsgt1