产品概述:Purified recombinant protein of Mouse integrin beta 6 (Itgb6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug蛋白长度:A DNA sequence from Mouse cDNA ORF Clone, [GM39861V], encoding Mouse full-length Itgb6.表达系统:HEK293T种属:Mouse标签类型:C-MYC/DDK分子量:86.5 kDa通用名:Itgb6总结:Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (PubMed:10025398). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:10025398).[UniProtKB/Swiss-Prot Function]形式:Liquid浓度:>50 ug/mL as determined by microplate BCA method纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.别名:2210409C20Rik; 4831415H04Rik