TIE2 (TEK) (NM_000459) Human R

产品概述：Purified recombinant protein of human TEK tyrosine kinase (TEK), endothelial, with C-terminal DDK/His tag, expressed in human cells, 20 µg 蛋白长度：A DNA sequence from GoldORF clone, [GH69045V], encoding the region (Ala23– Leu748) of human TEK 表达系统：HEK293 种属：Human 标签类型：C-DDK/His 分子量：84 kDa 通用名：TEK 总结：This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：PBS, pH7.4, 10% glycerol 别名：CD202B; GLC3E; TIE-2; TIE2; VMCM; VMCM1