EGFR (NM_201283) Human Recombi

产品概述：Purified recombinant protein of Homo sapiens epidermal growth factor receptor vIII (EGFR vIII) extracellular domain, residues Leu25-Ser378, with C-terminal DDK/His tag, expressed in HEK293 cells. 蛋白长度：A DNA sequence from GoldORF clone, [GH44488V], encoding the extracellular domain (Leu25 - Ser378) of human epidermal growth factor receptor vIII (EGFR vIII) 表达系统：HEK293 种属：Human 标签类型：C-DDK/His 分子量：41 kDa 通用名：EGFR 总结：The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：PBS, pH7.4, 10% glycerol 别名：ERBB; ERBB1; ERRP; HER1; mENA; NISBD2; PIG61