产品概述:Recombinant protein of human cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B), full length, with C-terminal DDK tag, expressed in sf9, 20ug蛋白长度:A DNA sequence from GoldORF clone, [GH31642V], encoding human full-length CDKN1B表达系统:Sf9种属:Human标签类型:C-DDK分子量:22.1 kDa通用名:CDKN1B总结:This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]形式:Liquid浓度:>50 ug/mL as determined by microplate BCA method纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining储存溶液:50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol别名:CDKN4; KIP1; MEN1B; MEN4; P27KIP1