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1-2年
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安诺伦（北京）生物科技有限公司
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文献和实验Microarray Approaches for Analysis of Tumor Suppressor Gene Function
tumor suppressor genes in human cancer (1 ) and hence one of the most exhaustively studied. Estimates based on a survey of p53 binding sites in the genome put the number of p53-regulated genes at several hundred (2 ), while the finding that p53
., Simeone, D.M., Shelton, A.A., Parmiani, G., Castelli, C., and Clarke, M.F. 2007b. Phenotypic characterization of human colorectal cancer stem cells. Proc. Natl. Acad. Sci. U.S.A. 104:10158‐10163.
Developing Genetically Engineered Mouse Models to Study Tumor Suppression
suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat. Genet. 29:418‐425. Joyner, A.L. 2001. Gene Targeting: A Practical Approach. Oxford
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