TdT (DNTT) (NM_001017520) Huma

产品概述：Purified recombinant protein of Human deoxynucleotidyltransferase, terminal (DNTT), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug 蛋白长度：A DNA sequence encoding human full-length DNTT 表达系统：E. coli 种属：Human 标签类型：N-GST and C-His 分子量：84.2 kDa 通用名：DNTT 总结：This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl. 别名：TDT