GADD45B (NM_015675) Human Reco

产品概述：Purified recombinant protein of Human growth arrest and DNA-damage-inducible, beta (GADD45B), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug 蛋白长度：A DNA sequence encoding full-length of GADD45B 表达系统：E. coli 种属：Human 标签类型：N-GST and C-His 分子量：45.6 kDa 通用名：GADD45B 总结：This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl. 别名：GADD45BETA; MYD118