Prealbumin (TTR) (NM_000371) H

产品概述：Purified recombinant protein of TTR, mutant Phe87Met/Leu110Met, expressed in E. coli, 50ug 蛋白长度：A DNA sequence from GoldORF clone, [GH34908V],encoding the region Gly21-Glu147 human full-length of TTR(Phe87Met/Leu110Met) 表达系统：E. coli 种属：Human 标签类型：Tag Free 分子量：13.6 kDa 通用名：TTR 总结：This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 90% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：PBS, 10%glycerol 别名：ATTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTN