PATZ1 Mouse Monoclonal Antibody [Clone ID: LBI2H4]

PATZ1 Mouse Monoclonal Antibod

y [Clone ID: LBI2H4]
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  • ¥690 - 2025
  • Leading Biology
  • 美国
  • 2025年07月09日
  • WB 1:2000
  • Mouse
  • Human, Mouse, Rat
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    • 详细信息
    • 技术资料
    • 靶点

      PATZ1

    • 浓度

      1 mg/ml

    • 应用范围

      WB 1:2000

    • 宿主

      Mouse

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

    • 亚型

      IgG2a

    • 免疫原

      Full length human recombinant protein of human PATZ1(NP_114440) produced in E.coli.

    • 规格

      100 ul/30 ul

    规格:100 ul产品价格:¥2025.0
    规格:30 ul产品价格:¥690.0
    别名:dJ400N23; MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG

    产品概述:PATZ1 mouse monoclonal antibody,clone LBI2H4

    总结:The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]

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