Androgen Receptor (AR) Mouse Monoclonal Antibody [Clone ID: LBI2H2]

Androgen Receptor (AR) Mouse M

onoclonal Antibody [Clone ID: LBI2H2]
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  • ¥690 - 2025
  • Leading Biology
  • 美国
  • 2025年07月11日
  • WB 1:2000
  • Mouse
  • Human, Mouse, Rat
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    • 详细信息
    • 技术资料
    • 靶点

      AR

    • 浓度

      1 mg/ml

    • 应用范围

      WB 1:2000

    • 宿主

      Mouse

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

    • 亚型

      IgG1

    • 免疫原

      Human recombinant protein fragment corresponding to amino acids 420-659 of human AR(NP_000035) produced in E.coli.

    • 规格

      100 ul/30 ul

    规格:100 ul产品价格:¥2025.0
    规格:30 ul产品价格:¥690.0
    别名:AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM

    产品概述:AR mouse monoclonal antibody, clone LBI2H2

    总结:The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

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