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- ￥690 - 2025
- Leading Biology
- AMM16210V
- 美国
- 2025年07月11日
- WB 1:2000, IHC 1:150
- Mouse
- Human
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- 文献和实验
- 技术资料
- 靶点：
ACE2
- 浓度：
1 mg/ml
- 应用范围：
WB 1:2000, IHC 1:150
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 标记物：
Unconjugated
- 克隆性：
Monoclonal Antibody
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态：
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
- 亚型：
IgG1
- 免疫原：
Human recombinant protein fragment corresponding to amino acids 18-237 of human ACE2 (NP_068576) produced in E.coli.
- 规格：
100 ul/30 ul
| 规格： | 100 ul | 产品价格： | ￥2025.0 |
|---|---|---|---|
| 规格： | 30 ul | 产品价格： | ￥690.0 |
产品概述：Purified ACE2 mouse monoclonal antibody, clone LBI1D6
总结：The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
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文献和实验Severe acute respiratory syndrome (SARS) coronavirus (CoV) contains a spike (S) protein that binds to a receptor molecule (angiotensin-converting enzyme 2; ACE2), induces membrane fusion, and serves as a neutralizing epitope. To study
14 Immunotargeting of Catalase to the Pulmonary Vascular Endothelium
. In order to provide catalase with such an affinity, catalase could be chemically conjugated with a carrier antibodies recognizing the surface endothelial antigens (8 ). A monoclonal antibody (MAb) against such an antigen, angiotensin-converting enzyme
AAV-hACE2构建新冠易感小鼠模型 | 突破转基因模型局限
. [2] Jiang RD, Liu MQ, Chen Y, et al. Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2. Cell. 2020;182(1):50-58.e8. [3] Israelow B, Song E, Mao T, et al. Mouse model of SARS-CoV-2 reveals inflammatory role of type
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