- ￥690 - 2025
- Leading Biology
- AMM14059V
- 美国
- 2025年07月13日
- WB 1:2000
- Mouse
- Human
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![ACAA2 Mouse Monoclonal Antibody [Clone ID: LBI3C6]](https://img1.dxycdn.com/2022/0707/344/1496323853485278553-14.jpg!wh200)
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
FAS
- 浓度：
1 mg/ml
- 应用范围：
WB 1:2000
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 标记物：
Unconjugated
- 克隆性：
Monoclonal Antibody
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态：
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
- 亚型：
IgG1
- 免疫原：
Full length human recombinant protein of human FAS(NP_000034) produced in HEK293T cell.
- 规格：
100 ul/30 ul
| 规格： | 100 ul | 产品价格： | ￥2025.0 |
|---|---|---|---|
| 规格： | 30 ul | 产品价格： | ￥690.0 |
产品概述：FAS mouse monoclonal antibody, clone LBI2C2
总结：The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011]
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文献和实验an important role in regulation of the immune system. In the method described, hepatoma MH134 (Fas− and FasL− ) is transfected with murine Fas and FasL cDNA. A single administration of monoclonal anti-Fas antibody efficiently suppresses the growth of F6b (MH134
Monoclonal Antibody Production
and screening of the hybridomas: 1. Bleeding Mice (1) Place the mouse in a mouse restrainer. (2) Sterilize the tail with 70% ethanol. (3) With a razor blade,nip off the last 2 mm of the tip of the tail. (4) Using a milking motion,pull blood down and let
Monoclonal Antibody Production
Monoclonal Antibody Production Mouse Immunization Order 6 six week old Balb/C mice and let the ARC know they are coming. Have your antigen ready for when they arrive. Once they get there earmark the mice and perform
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