p15 INK4b (CDKN2B) Mouse Monoclonal Antibody [Clone ID: LBI8H4]

p15 INK4b (CDKN2B) Mouse Monoc

lonal Antibody [Clone ID: LBI8H4]
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  • ¥690 - 2025
  • Leading Biology
  • 美国
  • 2025年07月13日
  • WB 1:500~2000, IHC 1:150, IF 1:100
  • Mouse
  • Human, Mouse, Rat
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    • 详细信息
    • 技术资料
    • 靶点

      CDKN2B

    • 浓度

      1 mg/ml

    • 应用范围

      WB 1:500~2000, IHC 1:150, IF 1:100

    • 宿主

      Mouse

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

    • 亚型

      IgG1

    • 免疫原

      Full length human recombinant protein of human CDKN2B(NP_004927) produced in HEK293T cell.

    • 规格

      100 ul/30 ul

    规格:100 ul产品价格:¥2025.0
    规格:30 ul产品价格:¥690.0
    别名:CDK4I; INK4B; MTS2; P15; p15INK4b; TP15

    产品概述:CDKN2B (p15 INK4b) mouse monoclonal antibody, clone LBI8H4

    总结:This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq]

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