MEK2 (MAP2K2) Mouse Monoclonal Antibody [Clone ID: LBI5F6]

MEK2 (MAP2K2) Mouse Monoclonal

Antibody [Clone ID: LBI5F6]
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  • ¥690 - 2025
  • Leading Biology
  • AMM09137V
  • 美国
  • 2025年07月11日
  • WB 1:2000, IHC 1:150, FLOW 1:100
  • Mouse
  • Human, Mouse, Rat
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    • 详细信息
    • 技术资料
    • 靶点

      MAP2K2

    • 浓度

      0.95 mg/ml

    • 应用范围

      WB 1:2000, IHC 1:150, FLOW 1:100

    • 宿主

      Mouse

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

    • 亚型

      IgG1

    • 免疫原

      Full-length protein expressed in 293T cell transfected with human MAP2K2 expression vector

    • 规格

      100 ul/30 ul

    规格:100 ul产品价格:¥2025.0
    规格:30 ul产品价格:¥690.0
    别名:CFC4; MAPKK2; MEK2; MKK2; PRKMK2

    产品概述:Anti-MAP2K2 (MEK2 ) mouse monoclonal antibody, clone LBI5F6

    总结:The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases.Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.

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