- 询价
- Excell Bio
- CB031-0043
- 中国
- 2025年12月16日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海依科赛生物制品有限公司
- 英文名：
EGF, human
- 规格：
1000ug
Product Sheet
EGF (Epithelial Growth Factor), human recombinantCatalog CB031-0043
Description The human Epithelial Growth Factor (EGF) is a growth factor important to proliferation of many types of cells, including stem cells.ExCell produces the full-length EGF in Escherichia coli as a single chain,
non-glycosylated, polypeptide with an apparent molecular mass of 6 kDa..
Source Escherichia coli. Endotoxin level of this product is lower than 0.1 EU/ug.
Formulation Lyophilized from sterile filtered PBS solution, carrier-free.
Reconstitution Before reconstitution, we recommend a brief spin to drive down any material dislodged from the bottom of the tube. It is recommended to reconstitute the lyophilized product in sterile water to no less than 100ug/ml. Further dilutions should be made in sterile buffer or medium containing carrier proteins, such as albumin or serum.
Stability The lyophilized protein is stable for at least 1 year if stored at -80 degree C.Reconstituted protein is stable for at least 2 week at 4 degree C, but should be stored in aliquots at -80 degree C for longer term. Avoid repeated freeze/thaw.
Purity Greater than 97% by SDS-PAGE analysis
Biological Activity The activity was determined by a cell proliferation assay of mouse fibroblasts. The EC50 ranges from 0.1 – 1.0 ng/ml.
For Research Use Only. Not for Use in Humans.
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文献和实验EGF受体是一种糖蛋白, 广泛分布于哺乳动物的上皮细胞、人的成纤维细胞、胶质细胞、角质细胞等。EGF 受体是一条含有1186个氨基酸残基的多肽链, 相对分子质量为170kDa,由三个部分组成:①很大的细胞外结构域：约621个氨基酸残基，富含半胱氨酸(51个), 并形成多对二硫键，其上结合有糖基,是EGF结合的位点。②跨膜区∶由23个氨基酸残基组成;③细胞质结构域,由542个氨基酸残基组成,含有无活性的酪氨酸激酶和几个酪氨酸磷酸化的位点。
webowner1985 如题。要是用一种药物处理细胞EGF分泌增多，请问参与促进EGF分泌的通路是什么呢？谢谢 zongjieli82 Cheung,W.Y., Zhai,R., Kulke,M., Heist,R., Asomaning,K., Ma,C., Wang,Z., Su,L., Christiani,D. and Liu,G. Epidermal Growth Factor A61G Gene
Expression of EGF and HIV Envelope Glycoprotein
This chapter reviews the expression of two proteins that are naturally secreted: murine epidermal growth factor (mEGF) and the 120-kDa envelope protein from human immunodeficiency virus (HIV-1 ENV). Although the initial aims of these projects
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