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玉研仪器公司
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MouseOx小动物生理监护仪,MouseOx® Plus pulse oximeter以无创的方式测量小动物(幼鼠,小鼠,大鼠,豚鼠,兔, 等)的血氧饱和度、脉搏频率、呼吸频率、脉搏幅度、呼吸幅度和体温。除体温外,所有测量都是通过一个无创的感应器。
主要应用:
• 动脉氧气饱和度,心率,呼吸率,脉搏舒张,呼吸舒张等参数的测量
• 动物麻醉状态、外科手术过程中作为监视设备
• 用于心肺功能的评价,连续监测心肺功能(心率在90-900 bpm),可作为心肺数据记录仪使用
• 新生动物体征的监测
• 肺损伤的研究,机械人工呼吸救助装置
• 休克动物模型的研究
• 中风和脑损伤的研究
• 转化型医学的研究
• 缺氧及吸入性实验的研究
• 确保动物处于适当的麻醉深度,预防手术中缺氧
MouseOx 系统包括三个组分: MouseOx设备、Starr链接模拟输出模块和Starr束缚管。
主要监测参数如下:
脉波频率(心率)
在90到900 BPM范围内监测(每分钟心跳, Beat per minutes, BPM)
血氧饱和度
监测范围: 0% 到100% 动脉血氧饱和度;
呼吸频率:
监测范围: 每分钟 25到450 次
动物体温
脉波幅度:
无创伤监测脉搏充盈度以估量血流量的变化.
呼吸幅度 (呼吸的动度)
无创伤监测动物呼吸幅度的变化.
经过验证的准确度
以下是使用有创血气采样测量结果与无创MouseOx测量结果的比较
可实现大鼠、小鼠清醒活动状态下进行测量
多种探头可选
软件界面
玉研仪器是美国STARR公司MouseOx授权中国总代理,美国Starr公司专注于实验动物(大鼠,小鼠)的无创监护,其mouseox是世界上第一款专门应用于小鼠和大鼠的监护仪,可以测量脉搏血氧,呼吸,心率,脉搏幅度,呼吸幅度,体温等参数。详情请来电咨询!
部分引用文献:
· Calibration and Validation of the MouseOx® Small-Animal Pulse Oximeter
Kingman P. Strohl* MD, David Baekey* PhD, Susan Dase** MS and Bernie Hete** PhD.
*Department of Pulmonary and Critical Care Medicine, Case Western Reserve University
**Department of Engineering, STARR Life Sciences Corp.
· Transfusion-related Acute Lung Injury
Chelsea A. Sheppard, MDa, Lennart E. Lo¨ gdberg, MD, PhDa, James C. Zimring, MD, PhDa, Christopher D. Hillyer, MDb,
aDepartment of Pathology and Laboratory Medicine, Room D-655, Emory University School of Medicine, 1364 Clifton Road, NE, Atlanta, GA 30322, USA
bDepartment of Pathology and Laboratory Medicine, Transfusion Medicine Program, Room D-655, Emory University Hospital, 1364 Clifton Road, NE, Atlanta, GA 30322, USAHEMATOLOGY/ONCOLOGY CLINICS OF NORTH AMERICA
· Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response
Adam T. Boutin,1 Alexander Weidemann,1 Zhenxing Fu,5 Lernik Mesropian,1
Katarina Gradin,2 Colin Jamora,1 Michael Wiesener,3 Kai-Uwe Eckardt,3 Cameron J. Koch,4 Lesley G. Ellies,5
Gabriel Haddad,5 Volker H. Haase,4 M. Celeste Simon,4 Lorenz Poellinger,2 Frank L. Powell,5 and Randall S. Johnson1
1Molecular Biology Section, Division of Biological Sciences, UC San Diego, La Jolla, CA 92093, USA
2Karolinska Institute, Stockholm S-17177, Sweden
3University of Erlangen, Erlangen D-91054, Germany
4University of Pennsylvania Medical School, Philadelphia, PA 19104, USA
5Departments of Medicine, Pediatrics, and Pathology, UC San Diego School of Medicine, La Jolla 92093 CA, USA
· Age-related cardiac muscle sarcopenia: Combining experimental
and mathematical modeling to identify mechanisms
Jing Lin a,b, Elizabeth F. Lopez a,c, Yufang Jin f, Holly Van Remmen d,e, Terry Bauch a, Hai-Chao Han g, Merry L. Lindsey a,b,d,e
aDivision of Cardiology, Department of Medicine, The University of Texas Health Science Center at San Antonio (UTHSCSA),
7703 Floyd Curl Dr., MC-7872, San Antonio, TX 78229, USA
bThe Janey Briscoe Center of Excellence in Cardiovascular Research, UTHSCSA, USA
cJohn Jay Science and Engineering Academy, UTHSCSA, USA
dThe Barshop Institute for Longevity and Aging Studies, UTHSCSA, USA
eDepartment of Cellular and Structural Biology, UTHSCSA, USA
fDepartment of Electrical Engineering, UTSA, USA
gDepartment of Mechanical Engineering, UTSA, USA
· Post infection A77-1726 blocks pathophysiologic sequelae of respiratory syncytial virus infection
Ian C. Davis1, Eduardo R. Lazarowski2, Fu-Ping Chen3, Judy M. Hickman-Davis1, Wayne M. Sullender3,4, and Sadis Matalon1,4,5
1 Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
2 Department of Medicine, UNC, Chapel Hill, NC, USA
3 Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
4 Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
5 Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
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· Calibration and Validation of the MouseOx® Small-Animal Pulse Oximeter
Kingman P. Strohl* MD, David Baekey* PhD, Susan Dase** MS and Bernie Hete** PhD.
*Department of Pulmonary and Critical Care Medicine, Case Western Reserve University
**Department of Engineering, STARR Life Sciences Corp.
· Transfusion-related Acute Lung Injury
Chelsea A. Sheppard, MDa, Lennart E. Lo¨ gdberg, MD, PhDa, James C. Zimring, MD, PhDa, Christopher D. Hillyer, MDb,
aDepartment of Pathology and Laboratory Medicine, Room D-655, Emory University School of Medicine, 1364 Clifton Road, NE, Atlanta, GA 30322, USA
bDepartment of Pathology and Laboratory Medicine, Transfusion Medicine Program, Room D-655, Emory University Hospital, 1364 Clifton Road, NE, Atlanta, GA 30322, USAHEMATOLOGY/ONCOLOGY CLINICS OF NORTH AMERICA
· Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response
Adam T. Boutin,1 Alexander Weidemann,1 Zhenxing Fu,5 Lernik Mesropian,1
Katarina Gradin,2 Colin Jamora,1 Michael Wiesener,3 Kai-Uwe Eckardt,3 Cameron J. Koch,4 Lesley G. Ellies,5
Gabriel Haddad,5 Volker H. Haase,4 M. Celeste Simon,4 Lorenz Poellinger,2 Frank L. Powell,5 and Randall S. Johnson1
1Molecular Biology Section, Division of Biological Sciences, UC San Diego, La Jolla, CA 92093, USA
2Karolinska Institute, Stockholm S-17177, Sweden
3University of Erlangen, Erlangen D-91054, Germany
4University of Pennsylvania Medical School, Philadelphia, PA 19104, USA
5Departments of Medicine, Pediatrics, and Pathology, UC San Diego School of Medicine, La Jolla 92093 CA, USA
· Age-related cardiac muscle sarcopenia: Combining experimental
and mathematical modeling to identify mechanisms
Jing Lin a,b, Elizabeth F. Lopez a,c, Yufang Jin f, Holly Van Remmen d,e, Terry Bauch a, Hai-Chao Han g, Merry L. Lindsey a,b,d,e
aDivision of Cardiology, Department of Medicine, The University of Texas Health Science Center at San Antonio (UTHSCSA),
7703 Floyd Curl Dr., MC-7872, San Antonio, TX 78229, USA
bThe Janey Briscoe Center of Excellence in Cardiovascular Research, UTHSCSA, USA
cJohn Jay Science and Engineering Academy, UTHSCSA, USA
dThe Barshop Institute for Longevity and Aging Studies, UTHSCSA, USA
eDepartment of Cellular and Structural Biology, UTHSCSA, USA
fDepartment of Electrical Engineering, UTSA, USA
gDepartment of Mechanical Engineering, UTSA, USA
· Post infection A77-1726 blocks pathophysiologic sequelae of respiratory syncytial virus infection
Ian C. Davis1, Eduardo R. Lazarowski2, Fu-Ping Chen3, Judy M. Hickman-Davis1, Wayne M. Sullender3,4, and Sadis Matalon1,4,5
1 Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
2 Department of Medicine, UNC, Chapel Hill, NC, USA
3 Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
4 Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
5 Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, AL 35233, USA