A synthesized peptide derived from human TSG101/VPS23
规格:
50 µl/100 µl/200 µl
规格:
50 µl
产品价格:
¥1650.0
规格:
100 µl
产品价格:
¥2685.0
规格:
200 µl
产品价格:
¥4230.0
分子量:Calculated MW: 44kDa
Observed MW: 44kDa
细胞定位:Cytoplasm, Late endosome membrane, Membrane, Nucleus, Peripheral membrane protein
稀释方法:WB 1:500 - 1:2000
总结:The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]