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- 2025年07月16日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
CEACAM8; CD66b; CD67; CGM6; NCA-95
- 浓度：
Affinity purification
- 宿主：
Rabbit
- 适应物种：
Human
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 保存条件：
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态：
形式：Liquid 储存溶液：Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- 亚型：
IgG
- 免疫原：
Recombinant fusion protein containing a sequence corresponding to amino acids 35-320 of human CEACAM8 (NP_001807.2).
- 规格：
50 µl/100 µl/200 µl
| 规格： | 50 µl | 产品价格： | ￥1425.0 |
|---|---|---|---|
| 规格： | 100 µl | 产品价格： | ￥2370.0 |
| 规格： | 200 µl | 产品价格： | ￥3930.0 |
Observed MW: Refer to figures
细胞定位：Cell membrane, GPI-anchor, Lipid-anchor
稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200
总结：Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8) is a single chain, GPI-anchored, highly glycosylated protein which belongs to the immunoglobulin superfamily and the carcinoembryonic antigen(CEA) family. CEACAM8 is expressed by neutrophils and eosinophils, and serves as a binding partner for CEACAM-6 and Galectin-3. It contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. Mature human CEACAM8 is a 287 amino acid GPI-linked glycoprotein. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells.
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