- ￥1425 - 3930
- Leading Biology
- APR29087N
- 美国
- 2025年07月10日
- Rabbit
- Human, Mouse, Rat
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- 详细信息
- 技术资料
- 靶点：
Ayu17-44; Ayu17-449; mKIAA1546; E130014J05Rik
- 浓度：
Affinity purification
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 保存条件：
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态：
形式：Liquid 储存溶液：Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- 亚型：
IgG
- 免疫原：
Recombinant protein of mouse TET2.
- 规格：
50 µl/100 µl/200 µl
| 规格： | 50 µl | 产品价格： | ￥1425.0 |
|---|---|---|---|
| 规格： | 100 µl | 产品价格： | ￥2370.0 |
| 规格： | 200 µl | 产品价格： | ￥3930.0 |
分子量：Calculated MW: 212kDa
Observed MW: 280KDa
稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200
总结：Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC into 5-hydroxymethylcytosine (5hmC and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC, and conversion of 5fC to 5-carboxylcytosine (5caC. Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.
Observed MW: 280KDa
稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200
总结：Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC into 5-hydroxymethylcytosine (5hmC and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC, and conversion of 5fC to 5-carboxylcytosine (5caC. Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.
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TET2 Rabbit pAb (APR29087N)
￥1425 - 3930
