- ￥1425 - 3930
- Leading Biology
- APR21974N
- 美国
- 2025年07月10日
- Rabbit
- Mouse, Rat
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- 详细信息
- 技术资料
- 靶点：
CRTC1; MECT1; TORC-1; TORC1; WAMTP1
- 浓度：
Affinity purification
- 宿主：
Rabbit
- 适应物种：
Mouse, Rat
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 保存条件：
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态：
形式：Liquid 储存溶液：Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- 亚型：
IgG
- 免疫原：
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CRTC1 (NP_056136.2).
- 规格：
50 µl/100 µl/200 µl
| 规格： | 50 µl | 产品价格： | ￥1425.0 |
|---|---|---|---|
| 规格： | 100 µl | 产品价格： | ￥2370.0 |
| 规格： | 200 µl | 产品价格： | ￥3930.0 |
分子量：Calculated MW: 62kDa/67kDa/68kDa
Observed MW: 80kDa
细胞定位：Cytoplasm, Nucleus
稀释方法：WB 1:200 - 1:2000
总结：Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
Observed MW: 80kDa
细胞定位：Cytoplasm, Nucleus
稀释方法：WB 1:200 - 1:2000
总结：Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
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CRTC1 Rabbit pAb (APR21974N)
￥1425 - 3930
