Coagulation factor III/Tissue Factor Rabbit pAb (APR20347N)

Coagulation factor III/Tissue

Factor Rabbit pAb (APR20347N)
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  • ¥1425 - 3930
  • Leading Biology
  • APR20347N
  • 美国
  • 2025年07月10日
  • Rabbit
  • Human, Mouse, Rat
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    • 详细信息
    • 技术资料
    • 靶点

      F3; CD142; TF; TFA

    • 浓度

      Affinity purification

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 保存条件

      Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      形式:Liquid 储存溶液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

    • 亚型

      IgG

    • 免疫原

      Recombinant fusion protein containing a sequence corresponding to amino acids 120-251 of human Coagulation factor III/Tissue Factor (NP_001984.1).

    • 规格

      50 µl/100 µl/200 µl

    规格:50 µl产品价格:¥1425.0
    规格:100 µl产品价格:¥2370.0
    规格:200 µl产品价格:¥3930.0
    分子量:Calculated MW: 27kDa/33kDa
    Observed MW: 53KDa/45KDa

    细胞定位:Membrane, Secreted, Single-pass type I membrane protein

    稀释方法:WB 1:500 - 1:2000
    IHC 1:50 - 1:200

    总结:This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.

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