Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
形态:
形式:Liquid 储存溶液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
亚型:
IgG
免疫原:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human PSMD4 (NP_002801.1).
规格:
50 µl/100 µl/200 µl
规格:
50 µl
产品价格:
¥1425.0
规格:
100 µl
产品价格:
¥2370.0
规格:
200 µl
产品价格:
¥3930.0
分子量:Calculated MW: 28kDa/40kDa
Observed MW: 50kDa
稀释方法:WB 1:500 - 1:2000
IF 1:50 - 1:200
IP 1:50 - 1:200
总结:The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21.