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- 详细信息
- 技术资料
- 靶点:
BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21; CAV1
- 浓度:
Affinity purification
- 应用范围:
WB (Mus musculus, Homo sapiens) IF (Mus musculus) IHC (Homo sapiens)
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat
- 保质期:
1-2年
- 供应商:
安诺伦(北京)生物科技有限公司
- 保存条件:
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态:
形式:Liquid 储存溶液:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- 亚型:
IgG
- 免疫原:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Caveolin-1 (NP_001744.2).
- 规格:
50 µl/100 µl/200 µl
| 规格: | 50 µl | 产品价格: | ¥1425.0 |
|---|---|---|---|
| 规格: | 100 µl | 产品价格: | ¥2370.0 |
| 规格: | 200 µl | 产品价格: | ¥3930.0 |
分子量:Calculated MW: 17kDa/20kDa
Observed MW: 20kDa/23kDa
细胞定位:Cell membrane, Golgi apparatus membrane, Membrane, Membrane raft, Peripheral membrane protein, caveola
稀释方法:WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
总结:The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Observed MW: 20kDa/23kDa
细胞定位:Cell membrane, Golgi apparatus membrane, Membrane, Membrane raft, Peripheral membrane protein, caveola
稀释方法:WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
总结:The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
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Caveolin-1 Rabbit pAb (APR22117N)
¥1425 - 3930




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