大家都在搜
手机验证
优利科(上海)生命科学有限公司
100
详询
科研
/
多克隆
详见说明书
1年
Anti-IFIT2
IFIT2抗体
详询
详询
/
见产品详情
IgG
冻干或液体
见产品详情
-20℃
1mg/ml
详询
英文名称 Anti-IFIT2 |
中文名称 干扰素诱导的三角形四肽重复蛋白2抗体 |
别 名 CIG-42; cig42; G10P2; GARG 39; Glucocorticoid attenuated response gene 39; IFI 54; IFI 54K; IFI-54K; IFI54; IFIT 2; IFIT-2; IFIT2; IFIT2_HUMAN; Interferon induced 54 kDa protein; Interferon induced protein 54; Interferon induced protein with tetratricopeptide repeats 2; Interferon, alpha inducible protein (MW 54kD); Interferon-induced 54 kDa protein; Interferon-induced protein with tetratricopeptide repeats 2; ISG 54 K; ISG 54K; ISG-54 K; ISG54. |
浓 度 1mg/1ml |
规 格 0.2ml/200μg |
抗体来源 Rabbit |
克隆类型 polyclonal |
交叉反应 Human, Mouse, Rat, Pig, Cow, Sheep |
产品类型 一抗 |
研究领域 细胞生物 免疫学 信号转导 细胞骨架 |
蛋白分子量 predicted molecular weight: 55kDa |
性 状 Lyophilized or Liquid |
免 疫 原 KLH conjugated synthetic peptide derived from human IFIT2 |
亚 型 IgG |
纯化方法 affinity purified by Protein A |
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
(石蜡切片需做抗原修复) |
not yet tested in other applications. |
optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
Function : IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. |
Subunit : Domain-swapped homodimer. Component of an interferon-dependent multiprotein complex, at least composed of IFIT1, IFIT2 and IFIT3. Interacts with IFIT1 and IFIT3. Interacts with TMEM173/MITA and disrupts its interaction with MAVS or TBK1. Interacts with EIF3E and EIF3C. |
Subcellular Location : Cytoplasm. Endoplasmic reticulum. |
Similarity : Belongs to the IFIT family. |
Contains 9 TPR repeats. |
Database links : UniProtKB/Swiss-Prot: P09913.1 |
PR (Progestogerone receptor) 孕激素受体(抗原) |
PS-1(NT),Presennillin-1(S182) 早老素蛋白-1(抗原) |
PS-1,Presennillin-1(CT) 早老素蛋白-1(S182) |
BYTA1(Breast cancer susceptbility gene 1)(mouse rat) 乳腺癌易感基因1抗原(小鼠 大鼠) |
BYTA1(Breast cancer susceptbility gene 1)(human) 乳腺癌易感基因1抗原(人) |
PSD-95 突触后密度蛋白95(抗原) |
PTP-1B (Protein-tyrosine phosphatase, non-receptor ) 蛋白酪氨酸磷酸酶-1B(抗原) |
RAR-α (Retinoic acid -R-α) 维甲酸受体-α 多肽 |
glycoprotein (E1 glycoprotein) [Rubella virus] 风疹病毒糖蛋白多肽片段 |
SAP (Synapse associated protein- I) 突触相关蛋白-1(抗原) |
SARS S-protein(抗原) |
SARS putative orflab polyprotein (SARS coronavirus CUHK-W1)(抗原) |
Secretin 分泌素(抗原) |
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
抗体使用小技巧.docx 附 (下载 0 次)