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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
100
- 靶点:
详询
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-phospho-IFNGR1 (Tyr457)
- 抗体名:
phospho-IFNGR1 (Tyr457)抗体
- 标记物:
详询
- 宿主:
兔
- 适应物种:
/
- 免疫原:
见产品详情
- 亚型:
IgG
- 形态:
冻干或液体
- 应用范围:
见产品详情
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-phospho-IFNGR1 (Tyr457) |
| 中文名称 干扰素gamma受体1蛋白抗体 |
| 别 名 Antiviral Protein Type II; Antiviral protein, type 2; AVP type II; AVP, type 2; CD 119; CD119; CDw119; CD119 antigen; CDw119; FLJ45734; IFN gamma R alpha; IFN gamma R; IFN gamma R1; IFN-gamma receptor 1; IFN-gamma-R1; IFNG R1; IFNGR 1; IFNGR; IFNGR1; Immune interferon receptor 1; Immune interferon receptor for; INGR1_HUMAN; Interferon gamma receptor 1; Interferon gamma receptor alpha chain; Interferon gamma receptor alpha chain precursor. |
| 浓 度 1mg/1ml |
| 规 格 0.1ml/100μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human |
| 产品类型 一抗 |
研究领域 微生物学 干细胞 细菌及 细胞表面分子 淋巴细胞 t-淋巴细胞 b-淋巴细胞 细胞因子 |
| 蛋白分子量 predicted molecular weight: 53kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human IFNGR1 (Tyr457) |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
| Function : Receptor for interferon gamma. Two receptors bind one interferon gamma dimer. |
| Subunit : Monomer. |
| Subcellular Location : Membrane; Single-pass type I membrane protein. |
| Post-translational modifications : Phosphorylated at Ser/Thr residues. |
| DISEASE : Mendelian susceptibility to mycobacterial disease (MSMD) [MIM:209950]: This rare condition confers predisposition to illness caused by moderately virulent mycobacterial species, such as Bacillus Calmette-Guerin (BCG) vaccine and environmental non-tuberculous mycobacteria, and by the more virulent Mycobacterium tuberculosis. Other microorganisms rarely cause severe clinical disease in individuals with susceptibility to mycobacterial infections, with the exception of Salmonella which infects less than 50% of these individuals. The pathogenic mechanism underlying MSMD is the impairment of interferon-gamma mediated immunity, whose severity determines the clinical outcome. Some patients die of overwhelming mycobacterial disease with lepromatous-like lesions in early childhood, whereas others develop, later in life, disseminated but curable infections with tuberculoid granulomas. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. Note=The disease is caused by mutations affecting the gene represented in this entry. |
| Similarity : Belongs to the type II cytokine receptor family. |
| Contains 2 fibronectin type-III domains. |
| Contains 2 Ig-like C2-type (immunoglobulin-like) domains. |
Database links : UniProtKB/Swiss-Prot: P15260.1![]() |
| IRS-3 胰岛素受体底物-3(抗原) |
| IRS-4 胰岛素受体底物-4(抗原) |
| IRS P53 (Insulin receptor suYTtrate P53)(多肽) |
| ITG-β3(Integrin β chain,β3 precursor) 整合素-β3(抗原) |
| Leptin 瘦素(多肽抗原) |
| Leptin receptor(long) 瘦素受体(长)(抗原) |
| MAPK-1/2 丝裂原活化蛋白激酶(抗原) |
| MAPKK2 丝裂原活化蛋白激酶激酶 |
| M2-PK ( pyruvate Kinase M2) 丙-酮酸激酶-M2(抗原) |
| M2-PK ( pyruvate Kinase M2 ) 丙-酮酸激酶-M2(抗原) |
| Melan-A/MART-1 黑色素-A(抗原) |
| ARIP2a(Activin receptor 2A) 激活素受体2A/激活素受体相互作用蛋白2a抗原 |
| β-arrestin 1/2(beta-arrestin 1/2) β-抑制蛋白1/2抗原 |
| ARIP2B(Activin receptor 2B) 激活素受体2B/激活素受体相互作用蛋白2b抗体 |
| MTR-1A (Melatonin receptor-1A) 褪黑素受体(抗原) |
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